Tipranavir: MedlinePlus Drug Information (2023)

pronounced as (tip ra' na veer)

  • Why is this medication prescribed?
  • How should this medicine be used?
  • Other uses for this medicine
  • What special precautions should I follow?
  • What special dietary instructions should I follow?
  • What should I do if I forget a dose?
  • What side effects can this medication cause?
  • What should I know about storage and disposal of this medication?
  • In case of emergency/overdose
  • What other information should I know?
  • Brand names


Tipranavir (taken with ritonavir [Norvir]) may cause bleeding in the brain. This condition may be life-threatening. Tell your doctor if you have recently had surgery, or if you have recently been injured in any way. Also, tell your doctor if you have a bleeding disorder such as hemophilia (condition in which the blood does not clot normally). Tell your doctor and pharmacist if you are taking any of the following medications: anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven), aspirin or products containing aspirin, cilostazol, clopidogrel (Plavix), dipyridamole (Persantine, in Aggrenox), eptifibatide (Integrilin), heparin, nonsteroidal anti-inflammatory drugs (ibuprofen, naproxen), prasugrel (Effient), ticlopidine, or tirofiban (Aggrastat). You should also tell your doctor and pharmacist if you are taking vitamin E, other than the amount contained in a regular daily multivitamin. If you need to get emergency medical treatment for any reason, be sure to tell all of the doctors who treat you that you are taking tipranavir. Call your doctor immediately if you experience unusual bruising or bleeding during your treatment with tipranavir.

Tipranavir (taken with ritonavir [Norvir]) may cause liver damage that may be life-threatening. Tell your doctor if you have or have ever had hepatitis (swelling of the liver caused by a virus), any other liver disease, or if you drink or have drunk alcohol. If you experience any of the following symptoms, stop taking tipranavir and call your doctor immediately: tiredness; weakness; flu-like symptoms; loss of appetite; nausea; vomiting; pain, ache, swelling, or sensitivity on your right side below your ribs; yellowing of the skin or eyes; dark (tea-colored) urine; or pale bowel movements.

Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests to check your body's response to tipranavir.

Talk to your doctor about the risks of taking tipranavir.

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Why is this medication prescribed?

Tipranavir is used with ritonavir (Norvir) and other medications to treat human immunodeficiency virus infection (HIV). Tipranavir is in a class of medications called protease inhibitors. It works by decreasing the amount of HIV in the blood. Although tipranavir does not cure HIV, it may decrease your chance of developing acquired immunodeficiency syndrome (AIDS) and HIV-related illnesses such as serious infections or cancer. Taking these medications along with practicing safer sex and making other lifestyle changes may decrease the risk of transmitting the HIV virus to other people.

How should this medicine be used?

Tipranavir comes as a capsule and an oral solution (liquid) to take by mouth. If tipranavir is taken with ritonavir capsules or solution, it is usually twice a day with or without food. If tipranavir is taken with ritonavir tablets, it is usually twice a day with meals. Take tipranavir and ritonavir at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take tipranavir exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Do not take tipranavir without ritonavir.

Swallow the capsules whole; do not chew or crush them. If you are unable to swallow the capsules, tell your doctor or pharmacist.

Tipranavir helps to control HIV infection but does not cure it. Continue to take tipranavir even if you feel well. Do not stop taking tipranavir without talking to your doctor. If you stop taking tipranavir or skip doses, your condition may become more difficult to treat. When your supply of tipranavir starts to run low, get more from your doctor or pharmacist.

Ask your doctor or pharmacist for a copy of the manufacturer's information for the patient. Read this information carefully and ask your doctor or pharmacist if you have any questions.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

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What special precautions should I follow?

Before taking tipranavir,

  • tell your doctor and pharmacist if you are allergic to tipranavir, ritonavir (Norvir, in Kaletra), sulfa medications, any other medications, or any of the ingredients in tipranavir capsules or solution. Ask your pharmacist if you are unsure if a medication you are allergic to is a sulfa medication. Also, ask your pharmacist for a list of the ingredients in tipranavir capsules or solution.
  • tell your doctor if you are taking any of the following medications or herbal products: alfuzosin (Uroxatral); cisapride (Propulsid) (no longer available in the U.S.); ergot medications for migraines such as dihydroergotamine (D.H.E. 45, Migranal), ergoloid mesylate (Hydergine), ergotamine (Ergomar, in Cafergot, in Migergot, others), or methylergonovine (Methergine); certain medications for irregular heartbeat including amiodarone (Nexterone, Pacerone), flecainide, propafenone (Rythmol), or quinidine (in Nuedexta); lovastatin (Altoprev), lurasidone (Latuda); midazolam by mouth; pimozide (Orap); rifampin (Rifadin, Rimactane, in Rifamate, in Rifater); sildenafil (Revatio) for treatment of pulmonary arterial hypertension, simvastatin (Zocor, in Vytorin); St. John's wort; and triazolam (Halcion). Your doctor will probably tell you not to take tipranavir if you are taking one or more of these medications.
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: antifungal medications such as fluconazole (Diflucan), itraconazole (Onmel, Sporanox), ketoconazole (Extina, Nizoral, Xolegel), or voriconazole (Vfend); boceprevir (no longer available in the U.S.; Victrelis); bosentan (Tracleer); calcium-channel blockers such as diltiazem (Cardizem, Cartia, Diltzac, Taztia, Tiazac, others), felodipine, nicardipine, nisoldipine (Sular), or verapamil (Calan, Covera, Verelan, others); cholesterol-lowering medications ('statins') such as atorvastatin (Lipitor, in Caduet) and rosuvastatin (Crestor); clarithromycin (Biaxin, in Prevpac); colchicine (Colcrys, Mitigare, in Col-Probenecid); desipramine (Norpramin); disulfiram (Antabuse); estrogen hormone replacement therapy; fluticasone (Flonase, Flovent, in Advair, in Dymista); immunosuppressants such as cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), or tacrolimus (Astagraf, Envarsus XR, Prograf, others); medications for diabetes such as glimepiride (Amaryl, in Duetact), glipizide (Glucotrol), glyburide (Diabeta, Glynase, others), pioglitazone (Actos, in Actoplus Met, in Duetact, in Oseni), repaglinide (Prandin, in Prandimet), or tolbutamide; certain medications for erectile dysfunction including sildenafil (Viagra), tadalafil (Adcirca, Cialis), or vardenafil (Levitra, Staxyn); certain medications for seizures including carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril), phenobarbital, phenytoin (Dilantin, Phenytek), and valproic acid (Depakene); other medications for HIV including abacavir (Ziagen, in Epzicom, in Trizivir), atazanavir (Reyataz, in Evotaz), dolutegravir (Tivicay, in Juluca), enfuvirtide (Fuzeon); etravirine (Intelence); fosamprenavir (Lexiva), lopinavir (in Kaletra), raltegravir (Isentress), and saquinavir (Invirase); meperidine (Demerol); methadone (Dolophine, Methadose); metronidazole (Flagyl, in Pylera); omeprazole (Prilosec, in Zegerid); quetiapine (Seroquel); rifabutin (Mycobutin); salmeterol (Serevent, in Advair); selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine (Prozac, Sarafem, Selfemra, in Symbyax), paroxetine (Brisdelle, Paxil, Pexeva), or sertraline (Zoloft); telaprevir (no longer available in the U.S.; Incivek); and trazodone. Many other medications may also interact with tipranavir, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Be sure to talk to your doctor or pharmacist before you begin taking any new medications during your treatment with tipranavir. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • if you are taking didanosine (Videx), take it 2 hours before or 2 hours after you take tipranavir.
  • if you are taking antacids, take them 1 hour before or 2 hours after you take tipranavir.
  • tell your doctor if you have or have ever had diabetes or high blood sugar; high blood cholesterol or triglycerides (blood fats); or an infection that comes and goes such as tuberculosis (TB), cytomegalovirus (CMV), herpes, Mycobacterium avium, shingles, or pneumonia.
  • you should know that some people with diabetes develop worsening of their diabetes while taking tipranavir. If you have diabetes, it is important to carefully monitor your blood sugar while taking tipranavir and call your doctor if your blood sugar becomes difficult to control. Your doctor may need to change your diabetes medication or prescribe new medication to control your blood sugar.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking tipranavir, call your doctor. Do not breastfeed if you are infected with HIV or are taking tipranavir.
  • you should know that tipranavir may decrease the effectiveness of hormonal contraceptives (birth control pills, patches, rings, and injections). You will need to use another method of contraception to prevent pregnancy while taking tipranavir. Talk to your doctor about other ways to prevent pregnancy while you are taking this medication.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking tipranavir.
  • plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Tipranavir may make your skin sensitive to sunlight.
  • you should know that your body fat may increase or move to different areas of your body such as the back of your neck and upper shoulders ('buffalo hump'), stomach, and breasts. Your body may lose fat from your arms, legs, face, and buttocks. Talk to your doctor if you notice any of these changes in your body fat.
  • you should know that you may experience hyperglycemia (increases in your blood sugar) while you are taking this medication, even if you do not already have diabetes. Tell your doctor immediately if you have any of the following symptoms while you are taking tipranavir: extreme thirst, frequent urination, extreme hunger, blurred vision, or weakness. It is very important to call your doctor as soon as you have any of these symptoms, because high blood sugar that is not treated can cause a serious condition called ketoacidosis. Ketoacidosis may become life-threatening if it is not treated at an early stage. Symptoms of ketoacidosis include dry mouth, nausea and vomiting, shortness of breath, breath that smells fruity, and decreased consciousness.
  • you should know that while you are taking medications to treat HIV infection, your immune system may get stronger and begin to fight other infections that were already in your body. This may cause you to develop symptoms of those infections. If you have new or worsening symptoms at any time during your treatment with tipranavir, be sure to tell your doctor.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

Take the missed dose together with ritonavir as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

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Tipranavir may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • diarrhea
  • weight loss
  • headache
  • stomach pain

Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately or get emergency medical treatment:

  • fever, chills, cough, or other signs of infection
  • rash
  • redness, blistering, or peeling of skin
  • itching
  • throat tightness
  • shortness of breath
  • weakness, numbness and pain, in hands and feet
  • difficulty breathing or swallowing
  • muscle or joint pain or stiffness

Tipranavir may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store unopened bottles of tipranavir capsules in the refrigerator. Store opened bottles of tipranavir capsules at room temperature, and away from excess heat and moisture (not in the bathroom). Store tipranavir solution at room temperature. Do not refrigerate or freeze tipranavir solution. Mark the date you open the bottle of tipranavir on the label; if the medication is not used within 60 days, dispose of the remaining medication.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

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In case of emergency/overdose

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to tipranavir.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand names

  • Aptivus®
Last Revised - 07/15/2020

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What medications should not be taken with Xarelto? ›

Some products that may interact with this drug include: mifepristone, other drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, "blood thinners" such as warfarin, enoxaparin), certain antidepressants (including SSRIs such as fluoxetine, SNRIs such as desvenlafaxine/venlafaxine).

What drugs should not be taken with ritonavir? ›

Key drug interactions: You should not take ritonavir with any of the following drugs: alfuzosin, amiodarone, astemizole, bepridil, avanafil, chlorazepate, cisapride, colchicine, diazepam, dihydroergotamine, dronedarone, elbasvir/grazoprevir, ergonovine, ergotamine, estazolam, flecanaide, flurazepam, fusidic acid, ...

What is the warning for ritonavir? ›

Ritonavir can cause serious, life-threatening side effects. These include inflammation of the pancreas (pancreatitis), heart rhythm problems, severe skin rash and allergic reactions, liver problems, and drug interactions.

Why was Xarelto taken off the market? ›

They noted that if you were on Xarelto and had spinal injections, epidurals, or surgery, you were at an increased risk of forming a blood clot in the spine that could cause paralysis. Further, the FDA noted that spinal clotting had increased for people on NSAIDs or patients with a history of spinal problems or surgery.

What fruits should you avoid if you are on blood thinners? ›

Grapefruit and other citrus fruits can interfere with how your body metabolizes these medications.

What does ritonavir do for COVID? ›

The trial demonstrated that starting ritonavir-boosted nirmatrelvir within 5 days of symptom onset in these patients reduced the risk of hospitalization or death through Day 28 by 89% compared to placebo.

Who Cannot use Paxlovid? ›

severe liver disease. had an organ transplant. certain autoimmune or inflammatory conditions (such as rheumatoid arthritis or inflammatory bowel disease) HIV or AIDS and have a weakened immune system.

What two drugs should not be taken together? ›

Specifically, drugs that slow down breathing rate, such as opioids, alcohol, antihistamines, CNS depressants, or general anesthetics, should not be taken together because these combinations increase the risk of life-threatening respiratory depression.

What does ritonavir do in the body? ›

It helps keep HIV from reproducing and appears to slow down the destruction of the immune system. This may help delay problems that are usually related to AIDS or HIV disease from occurring. Ritonavir will not keep you from spreading HIV to other people.

How long is ritonavir in your system? ›

Ritonavir half-life to 72 h was 6.84 h with darunavir and 6.07 with atazanavir. This study investigated the pharmacokinetic forgiveness of two boosted protease inhibitors.

Is ritonavir the same as Paxlovid? ›

Paxlovid (nirmatrelvir / ritonavir) is used to treat mild-to-moderate COVID-19 symptoms in people who have at least one these risk factors. If you're not sure whether you have a risk factor for severe illness, talk to your healthcare provider.

What is the number one prescribed blood pressure medicine? ›

The most common high blood pressure medications by total prescriptions written include: Lisinopril (Prinivil, Zestril): This medication is an angiotensin-converting enzyme (ACE) inhibitor. It is a drug that you usually take once per day. Most people find once-daily dosing to be convenient and easy to remember.

What is the safest high blood pressure pill? ›

the ACE inhibitor lisinopril (Prinivil, Zestril) tops the list, followed by amlodipine besylate (Norvasc), a calcium channel blocker, and.

What is the healthiest blood pressure medication? ›

There is a long list of medications for high blood pressure, and guidelines recommend both ACE inhibitors and ARBs as first-line options. Both classes have been proven effective in lowering blood pressure and curbing the risks of heart disease and stroke.

What is the safest blood thinner to use? ›

A new study published in November 2022 in Annals of Internal Medicine found apibaxan to be the safest blood thinner among DOACs, including dabigatran, edoxaban and rivaroxaban. Apibaxan was associated with the lowest risk of gastrointestinal bleeding.

Is there a safer alternative to Xarelto? ›

Eliquis, warfarin, Pradaxa, Plavix, and Brilinta are some Xarelto alternatives.

Is there a better blood thinner than Xarelto? ›

There is strong evidence that the medication apixaban (Eliquis) is preferable to rivaroxaban (Xarelto) for stroke prevention in patients with atrial fibrillation (AF), with both reduced rates of severe bleeding complications as well as strokes, according to study published Dec. 21 in JAMA.

Can you eat peanut butter on blood thinners? ›

Drug Interactions:

It might as well amplify the side effects of blood thinners. These side effects include abdominal pain, nosebleeds, blood in the urine, easy bruising (hematuria), and heavy menstrual bleeding. So, if you are on blood thinners, you should not consume peanut butter.

Are eggs OK on blood thinners? ›

On the positive side, patients are able to consume many foods considered safe if they are taking any anticoagulants. These are the foods that are considered safe to consume: Meat, fish, and eggs. Milk, cheese, and yogurt.

Can you eat salad on blood thinners? ›

Those who are prescribed a blood thinner, such as Coumadin, are told to avoid foods high in Vitamin K because this will counteract the effects of the blood thinner. Leafy vegetables (e.g. kale, collards, turnip greens, swiss chard, salad greens, parsley, spinach) are the highest sources of vitamin K.

What is the most effective drug in treating COVID-19? ›

Recommended use: The National Institutes of Health (NIH) recommends Paxlovid as the first-choice treatment for mild-to-moderate COVID-19 in people ages 12 and older who are at high risk for severe illness.

Does Paxlovid make you feel better? ›

Paxlovid pills are large, and swallowing them with a sore throat was difficult. But Lynda's throat began to feel better within a few hours of taking the medication. “It absolutely worked; it was effective, she says. “Within 24 hours, [my symptoms were] in a tolerable state.”

Can anyone take Paxlovid? ›

Paxlovid isn't authorized for everyone. This medication should only be prescribed to adults and children — ages 12 and older and weighing at least 88 pounds (40 kg) — who meet the following criteria: Have mild to moderate COVID-19 symptoms.

Is Paxlovid bad for your kidneys? ›

PAXLOVID is not recommended in patients with severe renal impairment (eGFR <30 mL/min) until more data are available; the appropriate dosage for patients with severe renal impairment has not been determined [see Use in Specific Populations (8.6) and Clinical Pharmacology (12.3)].

What are the dangers of Paxlovid? ›

A. Possible side effects of Paxlovid include dysgeusia (altered or impaired sense of taste), diarrhea, increased blood pressure, and myalgia (muscle aches). Allergic reactions, abdominal pain, nausea, and malaise (feeling generally unwell) have also been reported after Paxlovid use.

Who is at high risk for Paxlovid? ›

Examples of high-risk patient characteristics include older adults (age 50 yr+), asthma, smoking (current or former), overweight, diabetes, pregnant, immune compromised, mental health disorders, substance use disorders, and cardiovascular disease. Paxlovid is taken twice daily for 5 days.

What medications should be avoided in the elderly? ›

Here are seven common types of anticholinergic medication that older adults should avoid, or use with caution:
  • Sedating antihistamines. ...
  • PM versions of over-the-counter (OTC) painkillers. ...
  • Medications for overactive bladder. ...
  • Medications for vertigo or motion sickness. ...
  • Medications for itching. ...
  • Medications for nerve pain.

Is it OK to take all my meds at the same time? ›

Taking too many medications at once can be counterproductive (and even dangerous)

What medications interfere with blood pressure medication? ›

Some common types of OTC medicines you may need to avoid include:
  • Decongestants, such as those that contain pseudoephedrine.
  • Pain medicines (NSAIDs), such as ibuprofen and naproxen.
  • Cold and influenza (flu) medicines. ...
  • Some antacids and other stomach medicines. ...
  • Some natural health products.

Does ritonavir suppress the immune system? ›

Anti-HIV drugs such as ritonavir slow down or prevent damage to the immune system, and reduce the risk of developing AIDS-related illnesses.

Does ritonavir cross the blood brain barrier? ›

It is also possible that ritonavir and/or lopinavir mediate direct neurotoxicity in the CNS. However, this is quite unlikely given the well-established inability of these drugs to cross the blood-brain barrier (Varatharajan and Thomas, 2009).

Why is ritonavir called a booster? ›

Ritonavir (RTV), initially used simply as an active drug, is now used at low dosages (100 mg once [QD] or twice daily [BID]) as a booster in PI-based regimens; this is due to the drug's inhibitory activity on various cytochrome P450 isoenzymes (5).

Do you have to take antiretroviral drugs forever? ›

Yes. ART is not a cure and the virus remains in your body, even if your viral load is undetectable. So you need to keep taking your HIV medicine as prescribed.

Why is ritonavir taken with food? ›

To ensure the medicine is absorbed into the bloodstream properly. Some medicines require food in the stomach and gut for the body to absorb them properly, such as the HIV medicine ritonavir.

Can ritonavir cause high blood pressure? ›

Conclusions: Treatment with lopinavir/ritonavir is significantly associated with elevated BP, an effect that appears to be mediated through an increase in BMI.

What is the newest antiviral for Covid? ›

Remdesivir is the only antiviral drug that is approved by the Food and Drug Administration (FDA) for the treatment of COVID-19.

What is the best medicine for Covid cough? ›

Use medications containing guaifenesin, such as Robitussin, Mucinex, and Vicks 44E. keeping you from getting rest. Coughing is useful because it brings up mucus from the lungs and helps prevent bacterial infections. People with asthma and other lung diseases need to cough.

How long are you contagious after Covid? ›

Those with severe COVID-19 may remain infectious beyond 10 days and may need to extend isolation for up to 20 days. People who are moderately or severely immunocompromised should isolate through at least day 20.

What is the safest blood pressure medication with the least side effects? ›

While the class of blood pressure-lowering medicines called angiotensin-converting enzyme (ACE) inhibitors may be prescribed more commonly, angiotensin receptor blockers (ARBs) work just as well and may cause fewer side effects.

What is the average blood pressure for a 70 year old? ›

Elderly blood pressure range for men and women

The American College of Cardiology (ACC) and the American Heart Association (AHA) updated their guidelines in 2017 to recommend men and women who are 65 or older aim for a blood pressure lower than 130/80 mm Hg.

What is the newest blood pressure medication to market? ›

Baxdrostat is an oral medication that targets a hormone called aldosterone that regulates the amount of salt in your body. Baxdrostat blocks an enzyme that your body needs to make aldosterone, explains study co-author Morris Brown, M.D., a professor of endocrine hypertension at the Queen Mary University of London.

What is the first drug of choice for high blood pressure? ›

The strongest body of evidence indicates that for most patients with hypertension, thiazide diuretics are the best proven first-line treatment in reducing morbidity and mortality.

What are the five best blood pressure medications? ›

There are five major categories of medications that have been proven effective in treating hypertension:
  • Thiazide diuretics.
  • Calcium channel blockers.
  • Angiotensin-converting enzyme (ACE) inhibitors.
  • Angiotensin receptor blockers (ARBs)
  • Beta blockers.
May 20, 2022

What is the best hypertension medication for elderly? ›

Angiotensin Receptor Blockers

ARBs are considered the alternative first-line treatment for hypertension in the elderly population when a diuretic is contraindicated. In elderly hypertensive patients with diabetes or HF, ARBs are considered first-line treatment and an alternative to ACE inhibitors.

Can you ever get off blood pressure medication? ›

As you lose weight, it may be possible to reduce your dose of blood pressure medication — or stop taking blood pressure medication completely. Never make changes to your blood pressure medication on your own, however. Talk to your health care provider first.

Which blood pressure meds are bad for kidneys? ›

Diuretics, or water pills, are used to treat conditions like high blood pressure, glaucoma, and edema, but as with all medications, they come with some risks. Popular diuretics include hydrochlorothiazide, furosemide, and spironolactone. They are associated with a risk for acute kidney injury.

Is it OK to take Tylenol while taking Xarelto? ›

You can take Tylenol (acetaminophen) instead but follow the directions on the box to make sure you don't take more than the recommended amount. 2. If you have a stomach ache, avoid taking Pepto Bismol, as it can make you more likely to bleed when you're on Xarelto.

Is it OK to take Tylenol with Xarelto? ›

What should you not take with Xarelto? Avoid most pain relievers or nonsteroidal anti-inflammatory drugs (NSAIDs), including aspirin, naproxen, Excedrin, and ibuprofen. If you need a pain-relieving medication, acetaminophen (Tylenol) does not have known interactions with Xarelto.

Can I take Tylenol or ibuprofen with Xarelto? ›

You should avoid using NSAIDs and Xarelto together, unless your doctor says it's safe to do so. If you're taking Xarelto, talk with your doctor before using an NSAID. They may suggest using a pain reliever that doesn't interact with Xarelto, such as acetaminophen.

Is it OK to take vitamin D with Xarelto? ›

Interactions between your drugs

No interactions were found between Vitamin D3 and Xarelto.

What is the best pain reliever to take with Xarelto? ›

Common over-the-counter pain medications (called (NSAIDs) such as ibuprofen (Advil®), naproxen (Aleve®), and aspirin may increase the risk of bleeding problems. Acetaminophen (Tylenol®) can be used for pain.

What vitamins should be avoided when on Xarelto? ›

While taking any of the medications listed above a patient should stop the following supplements: fish oil, krill oil, vitamin E, garlic, and bromelaine. If you are taking a supplement that claims to have anti-‐inflammatory properties it must be approved by the doctor first.

What is the best blood thinner for the elderly? ›

Anticoagulants are the most common blood thinners prescribed to seniors. A popular one is warfarin, which goes by the brand names Coumadin and Jantoven and is administered in pill form. Popular alternatives to warfarin include dabigatran (Pradaxa), rivaroxiban (Xarelto) and apixaban (Eliquis).

What is the most common side effect of Xarelto? ›

Xarelto is a blood thinner used to treat and prevent blood clots. The most common side effect of Xarelto is bleeding, but it can also cause stomach pain and itchy skin. If you have signs or symptoms of mild bleeding while taking Xarelto, such as nose bleeds or light bruising, contact your healthcare provider.

How long can you stay on Xarelto? ›

For prevention of blood clots in people who are hospitalized for an acute illness: Adults—10 milligrams (mg) once a day in hospital and after hospital discharge for a total recommended duration of 31 to 39 days, taken with or without food. Children—Use and dose must be determined by your doctor.

Why does Xarelto cause leg pain? ›

People who undergo a spinal procedure while taking an anticoagulant like Xarelto have an increased risk of developing a spinal epidural hematoma. While rare, spinal or epidural blood hematomas can form rapidly and cause severe pain at the site locally while also radiating through the lower back and to the legs or arms.

What not to do while on blood thinners? ›

Because you are taking a blood thinner, you should try not to hurt yourself and cause bleeding. You need to be careful when you use knives, scissors, razors, or any sharp object that can make you bleed. You also need to avoid activities and sports that could cause injury. Swimming and walking are safe activities.

Can I take Xarelto in the morning with breakfast? ›

rivaroxaban 2.5 mg and 10 mg tablets can be taken with or without food.

What are the symptoms if your blood is too thin? ›

Thin blood means having too few platelets, a part of the blood that helps clots form.
Symptoms of thin blood include :
  • slow wound clotting.
  • bleeding gums.
  • nosebleeds.
  • blood in the stools.
  • heavy menstrual flow without clots.

Should Xarelto be taken at night or in the morning? ›

To reduce your risk of an AFib-related stroke, you should take XARELTO® once a day with your evening meal. If you miss a dose of XARELTO®, take it as soon as you remember on the same day.

What vitamins should be avoided when on blood thinners? ›

If you are a heart patient who is taking blood thinners, such as warfarin (Coumadin®), you need to be careful not to overdo vitamin K. Blood thinners are often prescribed for people at risk for developing harmful blood clots. If you suddenly increase your intake of vitamin K, it can have an unintended consequence.

What medications Cannot mix with vitamin D? ›

Phenobarbital, phenytoin, and other anticonvulsant medications -- These medications may accelerate the body's use of vitamin D. Mineral oil -- Mineral oil also interferes with absorption. In addition, Vitamin D may enhance the effects of doxorubicin , a medicine used to treat a variety of cancers.


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